爱游戏app赞助的罗马

王衡

王衡硕士生导师

 学科:基础兽医学        
电话/传真:020-85280234
电子邮件:wangheng2009@scau.edu.cn
通讯地址:广州市天河区五山路483号爱游戏app赞助的罗马 510642        
教研室:解剖组胚病理教研室
简介


  王衡,兽医病理学博士,副教授。2009年于东北农业大学获得兽医病理学博士学位,此后任职于爱游戏app赞助的罗马。广东省高等院校优秀青年教师,广东省畜牧兽医学会杰出科技工作者,国家非洲猪瘟区域实验室(广州)、华南农业大学动物疾病检测诊断中心成员,广东省畜牧兽医学会猪病学专业委员会秘书。主要从事猪病诊断与防控、猪场生物安全、重要病毒性猪病发病机制等研究。

  美国弗吉尼亚理工大学访问学者。主持国家基金、教育部、广东省科技厅、广东省教育厅科研项目多项。作为第一作者或通讯作者发表国外期刊收录论文20篇,中文核心期刊收录论文近30篇。作为主要完成人获得授权发明专利6项。兼任中国兽医病理学家学会成员、广东省畜牧兽医学会猪病学专业委员会秘书。


学历及培训经历


2014年 06月-2015年 06月美国弗吉尼亚理工大学(Virginia Polytechnic Institute and State University),访问学者 (Visiting Scholar)

2004年 07月-2009年 06月东北农业大学动物医学爱游戏app赞助的罗马博士研究生

1999年 09月-2004年 06月东北农业大学动物医学爱游戏app赞助的罗马本科生


工作经历


2009年07月至今爱游戏app赞助的罗马病理教研室讲师(2009)、副教授(2013)。


研究领域


?    畜禽疾病病理学研究

?    重要猪病发病机制、检测方法、流行病学与防控方法的研究


承担科研项目情况


?    国家自然科学基金重点项目:II型PRRSV重要抗原表位的筛选及其生物学功能的研究(31201876)

?    广东省自然科学基金项目:长链非编码RNA NEAT1与PRRSV相互作用机制的研究 (2018A030313712)

?    高等爱游戏app赞助的罗马博士学科点专项科研基金:猪戊型肝炎病毒ORF2段抗原模拟表位多肽的筛选与鉴定(20114404120010)

?    广东省农业攻关项目:应用II型PRRSV特异性结合多肽进行病毒检测方法的研究(2012B020306004)

?    广东省教育厅育苗工程项目:猪戊型肝炎病毒ORF2段抗原模拟表位的筛选及其活性的鉴定(2012LYM_0031)


代表论著(*通讯作者)


(1) ChiHai Ji, JingZhe Jiang, YingFang Wei, ZhiYuan Wang,YongJie Chen, ZhanZhuo Mai, MengKai Cai, ChenXiao Qin, Yu Cai, HeYou Yi, Guan Liang, Gang Lu, Lang Gong, GuiHong  Zhang* and Heng Wang(corresponding author). A Method for the Analysis of African Swine Fever by Viral Metagenomic Sequencing.  Fromtiers in Veterinary Science. 2021.8:766533 

(2) Zhao Huang, Lang Gong, Zezhong Zheng, Qi Gao, Xiongnan Chen, Yang Chen, Xiaojun Chen, Runda Xu, Jiachen Zheng, Zhiying Xu, Shengxun Zhang, Heng Wang(corresponding author), Guihong Zhang*. GS-441524 inhibits African swine fever virus infection in vitro. ANTIVIRAL RESEARCH. 2021,109: 105081 

(3) Hengxiao Zhai, Chihai Ji, Maria Carol Walsh, Jon Bergstrom, Sebastien Potot*, Heng Wang(corresponding author). The Addition of Nature Identical Flavorings Accelerated the Virucidal Effect of Pure Benzoic Acid against African Swine Fever Viral Contamination of Complete Feed. Animals (Basel). 2021 Apr 14;11(4):1124.doi:10.3390/ani11041124.

(4) Yingnan Liu, Yao Li, Zhenhua Xie, Qingying Ao, Dongdong Di, Wanqi Yu, Lu Lv, Qiuping Zhong, Yingying Song, Xinxin Liao, Qingqing Song, Heng Wang(corresponding author), Hongjun Chen*. Development and in vivo evaluation of MGF100-1R deletion mutant in an African swine fever virus Chinese strain,Vet Microbiol. 2021 Oct;261:109208. doi: 10.1016/j.vetmic.2021.109208.

(5) Wang Jingyu#; Gong Lang#; Zhang Weidong#; Chen Wanli; Pan Haoming; Zeng Yuchen; Liang Xingling; Ma Jun; Zhang Guihong*; WANG Heng (corresponding author). Wnt/β-catenin signaling pathway inhibits porcine reproductive and respiratory syndrome virus replication by enhancing the nuclear factor-κB-dependent innate immune response, Veterinary Microbiology, 2020, 251(108904).

(6) Ji Chihai, Wer Yingfang, Zeng Meng, Zhang Guihong*, WANG Heng (corresponding author). Development of a Dual Fluorescent Microsphere Immunological Assay for Detection of Pseudorabies Virus gE and gB IgG Antibodies. Viruses 2020, 12, 912. (IF=3.816)

(7) Yu, Zhi-Qing; Yi, He-You; Ma, Jun; Wei, Ying-Fang; Cai, Meng-Kai; Li, Qi; Qin, Chen-Xiao; Chen, Yong-Jie; Han, Xiao-Liang; Zhong, Ru-Ting; Chen, Yao; Liang, Guan; Deng, Qiwei; Tian, Kegong; WANG Heng (corresponding author); Zhang, Gui-Hong*; Ginsenos ide Rg1 Suppresses Type 2 PRRSV Infection via NF-kappaB Signaling Pathway In Vitro, and Provides Partial Protection against HP-PRRSV in Piglet. , Viruses-Basel, 2019, 11(11.)

(8) Sun YK, Han XL, Wei YF, Yu ZQ, Ji CH, Li Q, Lu G, Shen L, Ma CQ, WANG Heng (corresponding author), Zhang GH. Phylogeography, hylodynamics and the recent outbreak of lineage 3 porcine reproductive and respiratory syndrome viruses in China. Transbound Emerg Dis. 2019 Sep;66(5):2152-2162.

(9) Sun YK, Li Q, Yu ZQ, Han XL, Wei YF, Ji CH, Lu G, Ma CQ, Zhang GH, WANG Heng (corresponding author). Emergence of novel recombination lineage 3 of porcine reproductive and respiratory syndrome viruses in Southern China. Transbound Emerg Dis. 2019 Jan;66(1):578-587  (IF=3.504)

(10) Zhang X, Li Y, Xiao S, Yang X, Chen X, Wu P, Song J, Ma Z, Cai Z, Jiang M, Zhang Y, Yang Y, Zhang Z, Zhou Z, Sheng J, WANG Heng (corresponding author). High-frequency mutation and?recombination?are responsible for the?emergence?of?novel?porcine reproductive and respiratory syndrome?virus in northwest?China. Arch Virol. 2019 Nov;164(11):2725-2733.

(11)Xinliang Fu, Bo Fang, Yixing Liu, Mengkai Cai, Junming Jun, Jun Ma, Dexin Bu, Lifang Wang, Pei Zhou, WANG Heng (corresponding author), Guihong Zhang. Newly emerged porcine enteric alphacoronavirus in southern China: Identification, origin and evolutionary history analysis. Infection, Genetics and Evolution.2018. 62: 179–187 (IF=2.545)

(12) Wanli Chen, Jin Cui, Jingyu Wang, Yankou Sun, Chihai Ji, Ruyue Song, Yuchen Zeng, Haoming Pan, Jinliang Sheng, Guihong Zhang, WANG Heng (corresponding author).Phages bearing specific peptides with affinity for porcine reproductive and respiratory syndrome virus GP4 protein prevent cell penetration of the virus. Veterinary Microbiology. 2018. 224: 43–49 (IF=2.524) 

(13) WANG Heng, Weidong Zhang, Honglang Gu, Wanli Chen, Meng Zeng, Chihai Ji, Ruyue Song, Guihong Zhang, Identification and characterization of two linear epitope motifs in hepatitis E virus ORF2 protein. PLoS ONE. 2017. 12(9): e0184947  (IF=2.77)  

(14) WANG Heng, Rongchang Liu, Weidong Zhang, Lingshuang Sun, Zhangyong Ning, Fangxiao Ji, Jin Cui, Guihong Zhang, Identification of epitopes on nonstructural protein 7 of porcine reproductive and respiratory syndrome virus recognized by monoclonal antibodies using phage-display technology. Virus Genes. 2017. 53: 623–635 (IF=1.435)

(15)WANG Heng, Rongchang Liu, Jin Cui, Shengchao Deng, Jiexiong Xie, Zhangyong Ning and Guihong Zhang. Characterization and utility of phages bearing peptides with affinity to porcine reproductive and respiratory syndrome virus nsp7 protein. J Viol Methods. 2015 .15; 222: 231-241. (IF=1.756) 

(16)WANG Heng, Fangxiao Ji, Huanbin Liang, Honglang Gu, Zhangyong Ning, Rongchang Liu and Guihong Zhang. A Proline-Rich Domain in the Genotype 4 Hepatitis E Virus orF3 C-Terminus Is Crucial for Downstream V105DLP108 Immunoactivity. PLoS ONE. 2015. 10(7): e0133282. (IF=3.04) 


授权发明专利


1)王衡、张桂红、曾梦、冀池海; 一种伪狂犬病毒gE和Gb IgG 抗体双重荧光微球免疫学检测方法, 2021-12-24,中国,201811192108.X.

2)王衡; 宋雪梅; 张桂红; 杨奎亮; 卢刚; 李中圣; 一种非洲猪瘟核酸试纸条检测试剂盒, 2020-10-23, 中国, ZL201910689509.4. 

3)王衡; 张桂红; 纪方晓; 冀池海; 曾梦; 陈万里; 一种猪PRRSV、SIV、HEV抗体的液相芯片多重检测试剂盒, 2018-5-1, 中国, ZL201611015332.2. 

4)王衡; 张桂红; 纪方晓; 陈济铛; 梁焕斌; 朱婉君; 古洪浪; 一种猪戊型肝炎病毒ORF2重组蛋白的制备方法及其ORF2蛋白和检测试剂盒, 2013-5-1, 中国, ZL20161101584 5.3. 

5)张桂红; 王衡; 记方晓; 孙彦阔; 冀池海; 曾梦; 一种猪H1N1亚型流感病毒血凝素重组蛋白的制备方法及该病毒抗体的液相芯片检测试剂盒, 2016-11-18, 中国, CN201611015852.3.  

6)张桂红; 王衡; 梁焕斌; 宁章勇; 古洪浪; 纪方晓; 戊型肝炎病毒抗体检验通用ELISA法及其应用, 2014-6-4, 中国, CN201310556500.9.


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